GABA transporter-1 deficiency confers schizophrenia-like behavioral phenotypes.
The mechanism underlying the pathogenesis of schizophrenia remains poorly understood.The hyper-dopamine and hypo-NMDA receptor hypotheses have been the most enduring ideas.Recently, emerging evidence implicates alterations of the major inhibitory system, GABAergic neurotransmission in the schizophrenic patients.However, verragio paradiso the pathop